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Gene Expression Data
Assay Details
Assay
Reference: J:293794 Durbin MD, et al., SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol. 2020 Aug 15;464(2):124-136
Assay type: RNA in situ
MGI Accession ID: MGI:7531362
Gene symbol: Shroom3
Gene name: shroom family member 3
Probe: Shroom3 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 9.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS15: fronto-nasal process Present 1A
TS15: mesenchyme derived from lateral plate Present Regionally restricted 1A , 1C Expression is seen in lateral and splanchnic mesoderm just dorsal to the cardiac outflow tract.
TS15: heart Absent 1C , 1A

Specimen 5F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: heart Present 5F

Specimen 5G: embryonic day 11.5; Dvl2tm1.2Wds/Dvl2tm1.2Wds (more )
Structure Level Pattern Image Note
TS19: heart Present 5G Expression levels are reduced in the mutant.

Specimen 5H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Present 5H

Specimen 5I: embryonic day 12.5; Dvl2tm1.2Wds/Dvl2tm1.2Wds (more )
Structure Level Pattern Image Note
TS20: heart Present 5I Expression levels are reduced in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory