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Gene Expression Data
Assay Details
Assay
Reference: J:223915 Suckale J, et al., PTBP1 is required for embryonic development before gastrulation. PLoS One. 2011;6(2):e16992
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7529368
Gene symbol: Col4a1
Gene name: collagen, type IV, alpha 1
Antibody: anti-collagen IV
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5b control: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: Reichert's membrane Present Regionally restricted 5b control Expression is in basement membranes including the Reichert's membrane of the yolk sac.
TS11: basement membrane Present Regionally restricted 5b control Expression is in basement membranes including the Reichert's membrane of the yolk sac.
TS11: yolk sac Present Regionally restricted 5b control Expression is in basement membranes including the Reichert's membrane of the yolk sac.

Specimen 5b null: embryonic day 7.5; Ptbp1tm1Msol/Ptbp1tm1Msol (more )
Structure Level Pattern Image Note
TS11: yolk sac Present Regionally restricted 5b PTBP1 null This mutant has an unusually extended area high in protein not resembling a membrane.

Specimen S4 control: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: Reichert's membrane Present Regionally restricted S4_collagen 4 section 2 control Expression is in basement membranes including the Reichert's membrane of the yolk sac.
TS11: basement membrane Present Regionally restricted S4_collagen 4 section 2 control Expression is in basement membranes including the Reichert's membrane of the yolk sac.
TS11: yolk sac Present Regionally restricted S4_collagen 4 section 2 control Expression is in basement membranes including the Reichert's membrane of the yolk sac.

Specimen S4 null 1: embryonic day 7.5; Ptbp1tm1Msol/Ptbp1tm1Msol (more )
Structure Level Pattern Image Note
TS11: yolk sac Present Regionally restricted S4_collagen 4 section 2 null 1 This mutant has an unusually extended area high in protein not resembling a membrane.

Specimen S4 null 2: embryonic day 7.5; Ptbp1tm1Msol/Ptbp1tm1Msol (more )
Structure Level Pattern Image Note
TS11: yolk sac Present Regionally restricted S4_collagen 4 section 2 null 2 This mutant has an unusually extended area high in protein not resembling a membrane.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory