Ptbp1^tm1Msol
Targeted Allele Detail

Summary

• Symbol: Ptbp1^tm1Msol
• Name: polypyrimidine tract binding protein 1; targeted mutation 1, Michele Solimena
• MGI ID: MGI:4868473
• Synonyms: PTBP1^loxP
• Gene: Ptbp1 Location: Chr10:79690502-79700269 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Ptbp1^tm1Msol page

Small size of Ptbp1^tm1Msol/Ptbp1^tm1Msol embryos

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166852
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (No functional change, Null/knockout, Reporter) Mutation: Insertion Mutation details: A cassette containing an FRT site, splice acceptor, IRES, lacZ gene, hygromycin resistance, STOP sequence, FRT site and loxP site was inserted upstream of exon 3. An additional loxP site was inserted upstream of exon 7. (J:223915)

Generation of the Ptbp1^tm1Msol allele

Expression

In Mice Carrying this Mutation:	69 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptbp1 Mutation: 34 strains or lines available

References

• Original: J:166852 Liu Y, et al., Tamoxifen-independent recombination in the RIP-CreER mouse. PLoS One. 2010;5(10):e13533
• All: 6 reference(s)