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Gene Expression Data
Assay Details
Assay
Reference: J:223915 Suckale J, et al., PTBP1 is required for embryonic development before gastrulation. PLoS One. 2011;6(2):e16992
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7529366
Gene symbol: Ptbp1
Gene name: polypyrimidine tract binding protein 1
Reporter: lacZ
Direct Detection
Results
Specimen 2 E6.5: embryonic day 6.5; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present 2_E6.5
TS9: embryo endoderm Present 2_E6.5
TS9: embryo mesoderm Present 2_E6.5
TS9: primitive endoderm Present 2_E6.5
TS9: ectoplacental cone Absent 2_E6.5

Specimen 2 E7.5: embryonic day 7.5; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS11: embryo ectoderm Present 2_E7.5
TS11: embryo endoderm Present 2_E7.5
TS11: embryo mesoderm Present 2_E7.5
TS11: primitive endoderm Present 2_E7.5
TS11: chorion ectoderm Absent 2_E7.5
TS11: ectoplacental cone Absent 2_E7.5
TS11: yolk sac mesoderm Absent 2_E7.5

Specimen 2 E7.5 mother: postnatal adult; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 2_E7.5 Expression is in the decidua surrounding the tip of the embryo.

Specimen 2 E8.5: embryonic day 8.5; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS13: embryo Present 2_E8.5 Expression is in almost all cells.

Specimen 2 E9: embryonic day 9.0; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS14: embryo Present 2_E9 Expression is in most cells.
TS14: future brain Present Regionally restricted 2_E9 Expression is in most cells and is absent in the roof of the future head.
TS14: tail bud Present Regionally restricted 2_E9 There is little or no expression in some structures in the tail.
TS14: primitive ventricle Absent 2_E9

Specimen 2 E12.5: embryonic day 12.5; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS20: embryo Present 2_E12.5 Expression is in most developing tissues and organs.
TS20: brain Present Regionally restricted 2_E12.5 Expression is in the cells lining the ventricles of the brain.
TS20: cartilage Present 2_E12.5
TS20: cerebral cortex subventricular zone Present 2_E12.5
TS20: heart Present 2_E12.5
TS20: lung Present 2_E12.5
TS20: medulla oblongata Present 2_E12.5
TS20: metanephros Present 2_E12.5
TS20: nasal cavity Present 2_E12.5
TS20: pituitary gland Present 2_E12.5
TS20: spinal cord Present 2_E12.5
TS20: thyroid gland Present 2_E12.5

Specimen 2 E16.5: embryonic day 16.5; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS24: embryo Present 2_E16.5 Expression is in most developing tissues and organs.
TS24: brain Present Regionally restricted 2_E16.5 Expression is in the cells lining the ventricles of the brain.
TS24: brown fat Present 2_E16.5
TS24: cartilage Present 2_E16.5
TS24: cerebral cortex subventricular zone Present 2_E16.5
TS24: heart Present 2_E16.5
TS24: inner ear Present 2_E16.5
TS24: lung Present 2_E16.5
TS24: medulla oblongata Present 2_E16.5
TS24: metanephros Present 2_E16.5
TS24: nasal cavity Present 2_E16.5
TS24: pituitary gland Present 2_E16.5
TS24: spinal cord Present 2_E16.5
TS24: thyroid gland Present 2_E16.5
TS24: trigeminal ganglion Present 2_E16.5
TS24: rib cartilage Present Regionally restricted 2_E16.5 Expression was high in the ventral rib cartilage but much lower in the dorsal rib bones that already showed a central cavity.

Specimen S3 E12.5: embryonic day 12.5; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS20: embryo Present S3_E12.5

Specimen S3 E16.5: embryonic day 16.5; Ptbp1tm1Msol/Ptbp1+ (more )
Structure Level Pattern Image Note
TS24: embryo Present S3_E16.5
TS24: skin Present S3_E16.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory