Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:330081 Chen S, et al., Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation. Cancer Discov. 2022 Oct 5;12(10):2434-2453
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7529047
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system:	Secondary antibody coupled to Alexa Fluor 488
Assay notes:	The antibody used recognizes the cleaved form of the protein.

Results

Specimen 1F WT: embryonic day 16.5 (more

)
Note: Double labeled: green - Casp3; red - Ly76 (assay MGI:7529048).

Structure	Level	Pattern	Image	Note
TS24: liver	Absent		1F WT top , 1F WT bottom

Specimen 1F Lztr1^-/-: embryonic day 16.5; Lztr1^{tm1c(EUCOMM)Wtsi}/Lztr1^{tm1c(EUCOMM)Wtsi} (more

)
Note: Double labeled: green - Casp3; red - Ly76 (assay MGI:7529048).

Structure	Level	Pattern	Image	Note
TS24: liver	Present	Widespread	1F Lztr1^-/- top , 1F Lztr1^-/- bottom

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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