About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:183829 Correa SM, et al., Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012 Apr;8(4):e1002569
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7524459
Gene symbol: Nr5a1
Gene name: nuclear receptor subfamily 5, group A, member 1
Antibody: Anti-Ad4bp/SF-1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1M Wt1+/+ XX: embryonic day 13.5 (more )
Note: Double labeled: green - Nr5a1; red - Pecam1 (assay MGI:7524458).
Structure Level Pattern Image Note
TS21: ovary Present Uniform 1M Expressed at fairly equal levels in all somatic cells.
Specimen 1N Wt1+/+ XY AKR: embryonic day 13.5 (more )
Note: Double labeled: green - Nr5a1; red - Pecam1 (assay MGI:7524458).
Structure Cell Type Level Pattern Image Note
TS21: interstitium of the testis Present 1N Expression was up-regulated in Sertoli cells within testis cords and in specific interstitial cells, while down-regulated in most other interstitial cells.
TS21: Sertoli cell Sertoli cell Present 1N Expression was up-regulated in Sertoli cells within testis cords and in specific interstitial cells, while down-regulated in most other interstitial cells.
Specimen 1O Wt1+/- XY AKR: embryonic day 13.5; Wt1tm1Jae/Wt1+ (more )
Note: Gonads differentiated as ovaries. Double labeled: green - Nr5a1; red - Pecam1 (assay MGI:7524458).
Structure Level Pattern Image Note
TS21: gonad Present Uniform 1O Expression was uniform in all somatic cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory