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Gene Expression Data
Assay Details
Assay
Reference: J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7521974
Gene symbol: Sst
Gene name: somatostatin
Results
Specimen 2F Som +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Present 2F Som +/+
Specimen 2F Som -/-: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Strong 2F Som -/- Expression markedly increased compared to control.
Specimen Som +/+ not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present
TS21: spinal cord Present Regionally restricted Expression in dorsal spinal cord.
Specimen Som -/- not shown: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present Regionally restricted Abnormal accumulation of expression in dorsal root entry zone.
TS21: spinal cord Present Regionally restricted No changes in expression in dorsal spinal cord compared to control.
Specimen 4G Som: embryonic day 13.5 (more )
Note: Double labeled: green - Sst; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: midbrain Present Regionally restricted 4G Pattern of expression distinct compared to Sst.
Specimen 4H Som: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Note: Double labeled: green - Sst; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: midbrain Present 4H Expression pattern not changed compared to control.
Specimen 4I/J Som: embryonic day 13.5 (more )
Note: Double labeled: green - Sst; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: retina Present Regionally restricted 4J , 4I Expression co-localized with Pou4f1 in subset of ganglion cells.
Specimen 4K Som: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Note: Double labeled: green - Sst; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: central nervous system Present 4K Expression unaltered compared to control. No ectopic expression in central nervous system.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory