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Gene Expression Data
Assay Details
Assay
Reference: J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7521972
Gene symbol: Calb2
Gene name: calbindin 2
Results
Specimen 2F Calret +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Present 2F Calret +/+
Specimen 2F Calret -/-: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Strong 2F Calret -/- Expression markedly increased compared to control.
Specimen Calret +/+ not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present
TS21: spinal cord Present Regionally restricted Expression in dorsal spinal cord.
Specimen Calret -/- not shown: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present No significant changes in expression compared to control.
TS21: spinal cord Present Regionally restricted No change in expression in dorsal spinal cord compared to wild type.
Specimen 4A Calret: embryonic day 13.5 (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: hindbrain Present Regionally restricted 4A Expression characterize distinct populations of neurons - expression in adjacent but non-overlapping cell populations.
TS21: midbrain Present Regionally restricted 4A Expression characterize distinct populations of neurons - expression in adjacent but non-overlapping cell populations.
TS21: thalamus Present Regionally restricted 4A Expression characterize distinct populations of neurons - expression in adjacent but non-overlapping cell populations.
Specimen 4B Calret: embryonic day 13.5 (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: midbrain Present Regionally restricted 4B Authors report distinct expression of Calb2 and Pou4f1.
Specimen 4C Calret: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: midbrain Present 4C No apparent change in expression compared to control.
Specimen 4D/E Calret: embryonic day 13.5 (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: retina Present Regionally restricted 4E , 4D Expression overlapping with Pou4f1. Subset of neurons co-express both Calb2 and Pou4f1.
Specimen 4F Calret: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: retina Present 4F No apparent change in expression compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory