About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type: RNA in situ
MGI Accession ID: MGI:7521944
Gene symbol: Irx1
Gene name: Iroquois homeobox 1
Probe: Irx1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A Irx1 +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vestibulo-cochlear ganglion Present 3A Irx1 +/+
TS21: glossopharyngeal ganglion Trace 3A Irx1 +/+ Weak to undetectable expression in trigeminal and IX ganglia.
TS21: trigeminal ganglion Trace 3A Irx1 +/+ Weak to undetectable expression in trigeminal and IX ganglia.
Specimen Irx1 +/+ not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Trace Weak to undetectable expression in dorsal root ganglion.
Specimen 3A Irx1 -/-: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: glossopharyngeal ganglion Strong 3A Irx1 -/- Expression markedly increased in trigeminal ganglion and IX/X complex compared to control.
TS21: trigeminal ganglion Strong 3A Irx1 -/- Expression markedly increased in trigeminal ganglion and IX/X complex compared to control.
TS21: vagus ganglion Strong 3A Irx1 -/- Expression markedly increased in trigeminal ganglion and IX/X complex compared to control.
Specimen Irx1 -/- not shown: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Trace Expression not increased in dorsal root ganglion compared to control
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory