Gata3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type:	RNA in situ
MGI Accession ID:	MGI:7521943
Gene symbol:	Gata3
Gene name:	GATA binding protein 3

Probe:	Gata3 cDNA2
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

3A GATA3 +/+ ©

Specimen 3A GATA3 +/+: embryonic day 13.5 (more

)

Structure	Level	Image	Note
TS21: vestibulo-cochlear ganglion	Present	3A GATA3 +/+
TS21: glossopharyngeal ganglion	Trace	3A GATA3 +/+	Weak to undetectable expression in trigeminal and IX ganglia
TS21: trigeminal ganglion	Trace	3A GATA3 +/+	Weak to undetectable expression in trigeminal and IX ganglia

Specimen GATA3 +/+ not shown: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: dorsal root ganglion	Trace			Weak to undetectable expression in dorsal root ganglion.

3A GATA3 -/- ©

Specimen 3A GATA3 -/-: embryonic day 13.5; Pou4f1^tm1Nat/Pou4f1^tm1Nat (more

)

Structure	Level	Image	Note
TS21: glossopharyngeal ganglion	Strong	3A GATA3 -/-	Expression markedly increased in trigeminal ganglion and IX/X complex compared to control.
TS21: trigeminal ganglion	Strong	3A GATA3 -/-	Expression markedly increased in trigeminal ganglion and IX/X complex compared to control.
TS21: vagus ganglion	Strong	3A GATA3 -/-	Expression markedly increased in trigeminal ganglion and IX/X complex compared to control.

Specimen GATA3 -/- not shown: embryonic day 13.5; Pou4f1^tm1Nat/Pou4f1^tm1Nat (more

)

Structure	Level	Pattern	Image	Note
TS21: dorsal root ganglion	Strong			Expression increased in dorsal root ganglion compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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