Rgs10 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type:	RNA in situ
MGI Accession ID:	MGI:7521941
Gene symbol:	Rgs10
Gene name:	regulator of G-protein signalling 10

Probe:	RGS10 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

2C RGS10 +/+ ©

Specimen 2C RGS10 +/+: embryonic day 13.5 (more

)

Structure	Level	Image	Note
TS21: glossopharyngeal ganglion	Strong	2C RGS10 +/+	Strong expression in trigeminal ganglion and IX/X ganglion.
TS21: trigeminal ganglion	Strong	2C RGS10 +/+	Strong expression in trigeminal ganglion and IX/X ganglion.
TS21: vagus ganglion	Strong	2C RGS10 +/+	Strong expression in trigeminal ganglion and IX/X ganglion.

Specimen RGS10 +/+ not shown: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: vestibulo-cochlear ganglion	Present			Endogenous expression in vestibulocochlear ganglion not increased.
TS21: dorsal root ganglion	Strong			Strong expression in dorsal root ganglion.

2C RGS10 -/- ©

Specimen 2C RGX10 -/-: embryonic day 13.5; Pou4f1^tm1Nat/Pou4f1^tm1Nat (more

)

Structure	Level	Image	Note
TS21: glossopharyngeal ganglion	Absent	2C RGS10 -/-	Expression fell to background levels in knockout embryos.
TS21: trigeminal ganglion	Absent	2C RGS10 -/-	Expression fell to background levels in knockout embryos.
TS21: vagus ganglion	Absent	2C RGS10 -/-	Expression fell to background levels in knockout embryos.

Specimen RGS10 -/- not shown: embryonic day 13.5; Pou4f1^tm1Nat/Pou4f1^tm1Nat (more

)

Structure	Level	Pattern	Image	Note
TS21: dorsal root ganglion	Absent			Expression fell to background levels in knockout embryos.
TS21: vestibulo-cochlear ganglion	Absent			Expression fell to background levels in knockout embryos.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23