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Gene Expression Data
Assay Details
Assay
Reference: J:229010 Wang J, et al., Yap and Taz play a crucial role in neural crest-derived craniofacial development. Development. 2016 Feb 1;143(3):504-15
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7518667
Gene symbol: Yap1
Gene name: yes-associated protein 1
Antibody: anti-Yap1
Detection system: Secondary antibody
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component mesenchyme derived from head mesoderm Present 1B , 1A
TS17: 1st branchial arch mandibular component mesenchyme derived from neural crest Present 1B , 1A
Specimen 1C: embryonic day 10.5; Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component mesenchyme derived from neural crest Weak 1D , 1C Expression in this mutant was reduced in cranial neural crest-derived cells but not in non-cranial neural crest derived cells.
TS17: 1st branchial arch mandibular component mesenchyme derived from head mesoderm Present 1C , 1D
Specimen S4C: embryonic day 10.5 (more )
Note: Double labeled: green - Yap1; red - Phospho-Histone 3.
Structure Level Pattern Image Note
TS17: neural tube Present S4D , S4C
Specimen S4G: embryonic day 10.5; Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - Yap1; red - Phospho-Histone 3.
Structure Level Pattern Image Note
TS17: neural tube Present S4H , S4G Expression in this mutant is the same as controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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