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Gene Expression Data
Assay Details
Assay
Reference: J:107401 Jadrich JL, et al., The TGF{beta} activated kinase TAK1 regulates vascular development in vivo. Development. 2006 Apr;133(8):1529-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7517198
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: anti-alphaSMA
Results
Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 3A
Specimen 3B: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 3B Expression illustrated that the compact myocardium and trabeculae appeared thin and disorganized in comparison with wild-type hearts.
Specimen 4C: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS15: vitelline blood vessel Present Regionally restricted 4C Expression is in the smooth muscle.
Specimen 4D: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: umbilical or vitelline vessel Weak Regionally restricted 4D This mutant has no mature vitelline vessels and the exisitng vessels have little expression.
Specimen 6A: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Present Regionally restricted 6A Expression is in the smooth muscle.
TS15: cardiac muscle tissue Present 6A
TS15: somite Present 6A
Specimen 6B: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Absent 6B
TS15: cardiac muscle tissue Present 6B
TS15: somite Present 6B
Specimen 6C: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Absent 6C
TS15: cardiac muscle tissue Present 6C
TS15: somite Present 6C
Specimen 6D: embryonic day 10.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Present Regionally restricted 6D Expression is in the smooth muscle.
TS17: cardiac muscle tissue Present 6D
TS17: somite Present 6D
Specimen 6E: embryonic day 10.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Present Single cells 6E This less severely affected mutant has a few loosely associated expressing cells.
TS17: cardiac muscle tissue Present 6E
TS17: somite Present 6E
Specimen 6F: embryonic day 10.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Absent 6F This more severely affected mutant has a complete absence of expression.
TS17: cardiac muscle tissue Present 6F
TS17: somite Present 6F
Specimen not shown WT: embryonic day 8.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS13: vascular element Trace
Specimen not shown delta/delta: embryonic day 8.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS13: vascular element Trace
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory