Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1.1(Acrv1-icre)Jcoc
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Julie Cocquet
MGI ID:	MGI:7514846
Synonyms:	Acrv1-iCre, Rosa26Acrv1-iCre
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1.1(Acrv1-icre)Jcoc page

Germline Transmission:	Earliest citation of germline transmission: J:338406
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6J

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Gt(ROSA)26Sortm1.1(Acrv1-icre)Jcoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Acrv1 (MGI:104590)   Mutation details: The cDNA of iCre recombinase gene under the control of the mouse Acrv1 promoter sequence and hygromycin-resistant cassette, flanked by flippase recognition target sites, was inserted into the Gt(ROSA)26Sor locus. After germline transmission, the mice were crossed with the Flp-deleter line to eliminate the hygromycin cassette. (J:338406)

Activity:	Tissue activity of this recombinase allele
Driver:	Acrv1 (mouse) Summary of all recombinase alleles driven by Acrv1. Comparative matrix view of recombinase activities Alliance mouse Acrv1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:338406 Gobe C, et al., Generation and Characterization of a Transgenic Mouse That Specifically Expresses the Cre Recombinase in Spermatids. Genes (Basel). 2023 Apr 27;14(5)
All:	1 reference(s)