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Gene Expression Data
Assay Details
Assay
Reference: J:278470 Acharya D, et al., TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis. Sci Rep. 2018 Oct 8;8(1):14908
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7514664
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3B Tip55+/+ Heart: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: heart Ambiguous 3B CC3 Heart top
Specimen 3B Tip55delta/delta Heart: embryonic day 8.5; Kat5tm2Tfaz/Kat5tm2Tfaz (more )
Structure Level Pattern Image Note
TS13: heart Present 3B CC3 Heart bottom Apoptotic cell staining appeared to be higher in the mutant heart, but the differences were not statistically significant.
Specimen 3B Tip55+/+ Neural Tube: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural tube Ambiguous 3B CC3 Neural Tube top
Specimen 3B Tip55delta/delta Neural Tube: embryonic day 8.5; Kat5tm2Tfaz/Kat5tm2Tfaz (more )
Structure Level Pattern Image Note
TS13: neural tube Present 3B CC3 Neural Tube bottom Cleaved Casp3 staining was significantly elevated in neural tube of the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory