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Gene Expression Data
Assay Details
Assay
Reference: J:167511 Liu Z, et al., Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. PLoS Genet. 2010;6(12):e1001251
Assay type: RNA in situ
MGI Accession ID: MGI:7514268
Gene symbol: Pth
Gene name: parathyroid hormone
Probe: Pth probe
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A I Pth: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: thymus/parathyroid primordium Present Regionally restricted 2A I Pth Expression specifically marked anterior-dorsal parathyroid domain, with clear interface at Foxn1-positive posterior/ventral thymus domain.
Specimen 2A II Pth: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: parathyroid gland Present 2A II Pth Expression in domain starting to separate from thymus domain.
TS21: foregut gland primordium Present Single cells 2A II Pth Expression in some cells located outside major parathyroid domain.
TS21: thymus primordium Absent 2A II Pth
Specimen 2A III Pth: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: parathyroid gland Present 2A III Pth
TS26: gland Present Clusters 2A III Pth Expression in small clusters of cells located between parathyroid and thymus, or directly assocated with thymus, in some cases under thymic capsule.
TS26: thymus Absent 2A III Pth
Specimen 2B E13.5 WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: parathyroid gland Present 2B E13.5 WT
TS21: foregut gland primordium Present Single cells 2B E13.5 WT Expression in some cells located outside major parathyroid domain.
TS21: thymus primordium Absent 2B E13.5 WT
Specimen 2B E14.5 WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: parathyroid gland Present 2B E14.5 WT
TS22: foregut gland primordium Present Single cells 2B E14.5 WT Expression in some cells located outside major parathyroid domain.
TS22: thymus primordium Absent 2B E14.5 WT
Specimen 2B E18.5 WT: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: parathyroid gland Present 2B E18.5 WT
TS26: gland Present Clusters 2B E18.5 WT Expression in small clusters of cells located between parathyroid and thymus, or directly assocated with thymus, in some cases under thymic capsule.
TS26: thymus Absent 2B E18.5 WT
Specimen 2B E13.5 Gcm2-/-: embryonic day 13.5; Gcm2tm1Kry/Gcm2tm1Kry (more )
Structure Level Pattern Image Note
TS21: thymus primordium Absent 2B E13.5 Gcm2-/- No expression in misplaced parathyroid cells.
Specimen 2B E14.5 Gcm2-/-: embryonic day 14.5; Gcm2tm1Kry/Gcm2tm1Kry (more )
Structure Level Pattern Image Note
TS22: thymus primordium Absent 2B E14.5 Gcm2-/- No expression in misplaced parathyroid cells.
Specimen 2B E18.5 Gcm2-/-: embryonic day 18.5; Gcm2tm1Kry/Gcm2tm1Kry (more )
Structure Level Pattern Image Note
TS26: thymus Absent 2B E18.5 Gcm2-/- No expression in misplaced parathyroid cells.
Specimen 2C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: gland Present Regionally restricted 2C Expression in small clusters of cells located between parathyroid and thymus, or directly assocated with thymus, in some cases under thymic capsule.
TS26: thymus Absent 2C
Specimen 129/B6 Wild-type not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: gland Present Regionally restricted Expression in small clusters of cells located between parathyroid and thymus, or directly assocated with thymus, in some cases under thymic capsule.
Specimen 2D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: parathyroid gland Present 2D
TS26: gland Present Regionally restricted 2D Expression in small clusters of cells located between parathyroid and thymus, or directly assocated with thymus, in some cases under thymic capsule.
TS26: thymus Absent 2D
Specimen 2E: embryonic day 18.5; Gcm2tm1Kry/Gcm2tm1Kry (more )
Structure Level Pattern Image Note
TS26: parathyroid gland Absent 2E
TS26: thymus Absent 2E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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