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Gene Expression Data
Assay Details
Assay
Reference: J:175773 Maxwell MM, et al., The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS. Hum Mol Genet. 2011 Oct 15;20(20):3986-96
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7511741
Gene symbol: Cnp
Gene name: 2',3'-cyclic nucleotide 3' phosphodiesterase
Antibody: anti-CNPase (clone 11-5B)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3C: postnatal month 5 (more )
Note: Double labeled: green - Cnp; red - Sirt2 (assay MGI:7511736).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum granule cell layer oligodendrocyte Present Regionally restricted 3C middle , 3C right CNP is an oligodendroglia marker. Co-immunoreactivity was seen with Sirt2 in fiber tracts, but not cell bodies.
Specimen S5a: postnatal adult (more )
Note: Double labeled: green - Cnp; red - Sirt2 (assay MGI:7511736).
Structure Cell Type Level Pattern Image Note
TS28: brain oligodendrocyte Present S5a middle , S5a right Expression in the oligodendrocyte. Co-expression with Sirt2 was not seen in the cell bodies.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory