Gene Expression Data
Assay Details
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Assay
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Reference:
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J:210131
Roy A, et al., Lhx2 regulates the development of the forebrain hem system. Cereb Cortex. 2014 May;24(5):1361-72
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7511702
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Gene symbol:
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Lhx5
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Gene name:
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LIM homeobox protein 5
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Probe:
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Lhx5 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4C Control:
embryonic day 12.5
(more  )
Specimen
4C Control:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Cajal-Retzius cell |
Present |
Regionally restricted |
4C Control
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Expressed in the septum.
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Specimen
4C -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lhx2tm1Dra/Lhx2tm1Dra
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Cajal-Retzius cell |
Present |
Regionally restricted |
4C -/-
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A considerable increase in the Cajal-Retzius cells accumulated at the septum.
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Specimen
7G:
embryonic day 11.5
(more )
Specimen
7G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
S2B Control:
embryonic day 12.5
(more )
Specimen
S2B Control:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Regionally restricted |
S2B left
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Expressed in the mantle of the thalamic eminence and the thin domain adjacent to the zona limitans intrathalamica.
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Specimen
S2B -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lhx2tm1Dra/Lhx2tm1Dra
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Regionally restricted |
S2B right
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Expressed in the mantle of the thalamic eminence, which was dramatically expanded in the mutant. Expression in the thin domain adjacent to the zona limitans intrathalamica appeared normal.
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| TS20: caudal ganglionic eminence |
Present |
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S2B right
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The caudal ganglionic eminence was morphologically greatly reduced in the mutant.
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Specimen
S4Bi:
embryonic day 10.5
(more )
Specimen
S4Bi:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
S4Biii:
embryonic day 10.5
(more )
Specimen
S4Biii:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: diencephalon |
Present |
Regionally restricted |
S4Biii
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Expressed in the thalamic eminence.
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Analysis Tools