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Gene Expression Data
Assay Details
Assay
Reference: J:191149 Alves CH, et al., Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7511531
Gene symbol: Glul
Gene name: glutamate-ammonia ligase
Antibody: Anti-Glutamine Synthetase Clone 6 (610518)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 10A: postnatal month 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-. Double labeled: green - Glul; red - Gfap (assay MGI:7511529).
Structure Level Pattern Image Note
TS28: retina Present 10E , 10A
Specimen 10B: postnatal month 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant. Double labeled: green - Glul; red - Gfap (assay MGI:7511529).
Structure Level Pattern Image Note
TS28: retina Present 10F , 10B
Specimen 10G: postnatal month 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-. Double labeled: green - Glul; red - Sox9 (assay MGI:7507167).
Structure Level Pattern Image Note
TS28: retina Present 10G
Specimen 10H: postnatal month 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant. Double labeled: green - Glul; red - Sox9 (assay MGI:7507167).
Structure Cell Type Level Pattern Image Note
TS28: retina outer nuclear layer Mueller cell Present 10H Ectopic Muller glia cells were detected in the mutant outer nuclear layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory