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Gene Expression Data
Assay Details
Assay
Reference: J:256987 Shi B, et al., MORC2B is essential for meiotic progression and fertility. PLoS Genet. 2018 Jan;14(1):e1007175
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7509241
Gene symbol: Morc2b
Gene name: microrchidia 2B
Antibody: anti-MORC2B (UP2419)
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Two Morc2b antibodies were described, but the one used in this assay was not detailed. Anti-MORC2B (UP2420) MGI:7509125 may have been used in this assay.
Results
Specimen 1D: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 1D merged , 1D MORC2B
TS28: spermatocyte Present Regionally restricted 1D merged inset , 1D MORC2B , 1D merged , 1D MORC2B inset Expression in meiotic spermatocytes, localized to nucleus.
TS28: spermatid Present Regionally restricted 1D MORC2B , 1D merged Abundant expression in post-meiotic haploid round spermatids, strongly localized to nucleus. Expression absent from elongated spermatids.
TS28: Sertoli cell Sertoli cell Absent 1D MORC2B , 1D merged No expression in somatic cells such as Sertoli cells.
Specimen 1E: postnatal adult; Morc2btm1Jw/Morc2btm1Jw (more )
Structure Level Pattern Image Note
TS28: testis Absent 1E MORC2B inset , 1E MORC2B , 1E merged , 1E merged inset
TS28: spermatocyte Absent 1E merged inset , 1E MORC2B inset , 1E merged , 1E MORC2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory