Gene Expression Data
Assay Details
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Assay
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Reference:
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J:234197
Wong BH, et al., Mfsd2a Is a Transporter for the Essential omega-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development. J Biol Chem. 2016 May 13;291(20):10501-14
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7507606
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Gene symbol:
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Aif1
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Gene name:
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allograft inflammatory factor 1
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Results
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Specimen
not shown:
postnatal day 14
(more  )
Specimen
not shown:
(close  )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal day 14
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina |
microglial cell |
Present |
Regionally restricted |
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Expression normally in inner eye.
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Specimen
6B:
(close )
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Genetic Background:
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B6.Cg-Mfsd2atm1Dls
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Mutant Allele(s):
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Mfsd2atm1Dls/Mfsd2atm1Dls
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Age:
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postnatal day 14
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6C WT:
postnatal day 14
(more )
Specimen
6C WT:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal day 14
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6C KO:
(close )
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Genetic Background:
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B6.Cg-Mfsd2atm1Dls
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Mutant Allele(s):
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Mfsd2atm1Dls/Mfsd2atm1Dls
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Age:
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postnatal day 14
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina |
microglial cell |
Present |
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6C KO Merge
,
6C KO Iba-1
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Expressing cels appear rounder and less ramified compared with wild type, indicative of an activated state.
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Analysis Tools