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Gene Expression Data
Assay Details
Assay
Reference: J:174198 Rainger J, et al., Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice. PLoS Genet. 2011 Jul;7(7):e1002114
Assay type: RNA in situ
MGI Accession ID: MGI:7506298
Gene symbol: Smoc1
Gene name: SPARC related modular calcium binding 1
Probe: Smoc1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3a: embryonic day 9.5 (more )
Note: Whole mount in situ hybridization combined with optical projection tomography.
Structure Level Pattern Image Note
TS15: branchial arch Present 3a
TS15: forelimb bud Present 3a
TS15: fronto-nasal process Present 3a
TS15: future hindbrain Present 3a
TS15: somite Present 3a
TS15: neural tube Present Regionally restricted 3a Expressed in the rostral region.
Specimen 3b/S1: embryonic day 10.5 (more )
Note: Whole mount in situ hybridization combined with optical projection tomography.
Structure Level Pattern Image Note
TS17: branchial arch Strong 3b
TS17: fronto-nasal process Strong 3b
TS17: neural tube Strong 3b Strong staining in the dorsal region. Expression extended caudally.
TS17: forelimb bud Present Regionally restricted S1a , 3b Expressed in both the dorsal and ventral surface.
TS17: hindlimb bud Present Regionally restricted S1b , 3b Expression was predominantly dorsal and with small region of ventral expression.
TS17: somite Present 3b
Specimen S1c: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye surface ectoderm Weak S1c Expressed in the surface ectoderm overlying the optic vesicles.
TS17: optic cup Absent S1c
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory