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Gene Expression Data
Assay Details
Assay
Reference: J:165898 Suzuki-Inoue K, et al., Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. J Biol Chem. 2010 Aug 6;285(32):24494-507
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7495703
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-CD31 (2H8 MAB1398Z)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3A/C: embryonic day 14.5 (more )
Note: Triple labeled: red - Pecam1; blue - Ly76/Ter-119 (assay MGI:7495704); green - Lyve1 (assay MGI:7495705).
Structure Cell Type Level Pattern Image Note
TS22: artery endothelium endothelial cell of artery Present 3A , 3C
TS22: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3C , 3A Lymphatic vessels were narrow, straight, and smooth appearance.
Specimen 3D/F: embryonic day 14.5; Clec1btm1.1Ksi/Clec1btm1.1Ksi (more )
Note: Triple labeled: red - Pecam1; blue - Ly76/Ter-119 (assay MGI:7495704); green - Lyve1 (assay MGI:7495705).
Structure Cell Type Level Pattern Image Note
TS22: artery endothelium endothelial cell of artery Present 3F , 3D Similar as in the wild-type.
TS22: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3D , 3F Lymphatic vessels were disorganized and distended in the mutant, with a dilated, tortuous, and rugged appearance.
Specimen 3G/I: embryonic day 14.5; Clec1btm1.1Ksi/Clec1btm1.1Ksi (more )
Note: Triple labeled: red - Pecam1; blue - Ly76/Ter-119 (assay MGI:7495704); green - Lyve1 (assay MGI:7495705).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3I , 3G Lymphatic vessels were disorganized and distended in the mutant, with a dilated, tortuous, and rugged appearance.
Specimen 3J/L: embryonic day 17.5; Clec1btm1.1Ksi/Clec1btm1.1Ksi (more )
Note: Triple labeled: red - Pecam1; blue - Ly76/Ter-119 (assay MGI:7495704); green - Lyve1 (assay MGI:7495705).
Structure Cell Type Level Pattern Image Note
TS25: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3J , 3L Lymphatic vessels were disorganized and distended in the mutant, with a dilated, tortuous, and rugged appearance.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory