About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:165898 Suzuki-Inoue K, et al., Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. J Biol Chem. 2010 Aug 6;285(32):24494-507
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7495705
Gene symbol: Lyve1
Gene name: lymphatic vessel endothelial hyaluronan receptor 1
Antibody: Anti-Lyve1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3B/C: embryonic day 14.5 (more )
Note: Triple labeled: green - Lyve1; blue - Ly76/Ter-119 (assay MGI:7495704); red - Pecam1 (assay MGI:7495703).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3B , 3C Lymphatic vessels were narrow, straight, and smooth appearance.
Specimen 3E/F: embryonic day 14.5; Clec1btm1.1Ksi/Clec1btm1.1Ksi (more )
Note: Triple labeled: green - Lyve1; blue - Ly76/Ter-119 (assay MGI:7495704); red - Pecam1 (assay MGI:7495703).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3F , 3E Lymphatic vessels were disorganized and distended in the mutant, with a dilated, tortuous, and rugged appearance and filled with erythrocytes.
Specimen 3H/I: embryonic day 14.5; Clec1btm1.1Ksi/Clec1btm1.1Ksi (more )
Note: Triple labeled: green - Lyve1; blue - Ly76/Ter-119 (assay MGI:7495704); red - Pecam1 (assay MGI:7495703).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3I , 3H Lymphatic vessels were disorganized and distended in the mutant, with a dilated, tortuous, and rugged appearance and filled with erythrocytes.
Specimen 3K/L: embryonic day 17.5; Clec1btm1.1Ksi/Clec1btm1.1Ksi (more )
Note: Triple labeled: green - Lyve1; blue - Ly76/Ter-119 (assay MGI:7495704); red - Pecam1 (assay MGI:7495703).
Structure Cell Type Level Pattern Image Note
TS25: lymphatic vessel endothelium endothelial cell of lymphatic vessel Present 3L , 3K Lymphatic vessels were disorganized and distended in the mutant, with a dilated, tortuous, and rugged appearance and filled with erythrocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory