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Gene Expression Data
Assay Details
Assay
Reference: J:324832 Sun Y, et al., Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022 Mar 22;38(12):110542
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7493888
Gene symbol: Casz1
Gene name: castor zinc finger 1
Reporter: HA
Antibody: anti-HA tag
Detection system: Secondary antibody
Results
Specimen S7G: embryonic day 13.5; Casz1em1Zyliu/Casz1+ (more )
Note: Double labeled: green - Casz1; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS22: cochlear ganglion neuron Present S7G' , S7G Expression is significantly higher in vestibular ganglionic cells than spiral ones.
TS22: vestibular ganglion neuron Present S7G' , S7G Expression is significantly higher in vestibular ganglionic cells than spiral ones.
Specimen S7H: embryonic day 13.5; Casz1em1Zyliu/Casz1+ (more )
Note: Double labeled: green - Casz1; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS22: cochlear ganglion neuron Present S7H
Specimen S7I: embryonic day 13.5; Casz1em1Zyliu/Casz1+ (more )
Note: Triple labeled: green - Casz1 reporter; red - Myo6 (assay MGI:7493892); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS22: utricle epithelium vestibular hair cell Present Punctate S7I
TS22: utricle neuron Present Punctate S7I
Specimen S7K: postnatal day 3; Casz1em1Zyliu/Casz1+ (more )
Note: Double labeled: green - Casz1; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS27: cochlear ganglion spiral ganglion neuron Present S7K Expression is significantly higher in vestibular ganglionic cells than spiral ones.
TS27: vestibular ganglion neuron Present S7K Expression is significantly higher in vestibular ganglionic cells than spiral ones.
Specimen S7K inset: postnatal day 3; Casz1em1Zyliu/Casz1+ (more )
Note: Triple labeled: green - Casz1 reporter; red - Map2 (assay MGI:7493890); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS27: cochlear ganglion spiral ganglion neuron Present S7K inset
Specimen S7L: postnatal day 10; Casz1em1Zyliu/Casz1+ (more )
Note: Triple labeled: green - Casz1 reporter; red - Map2 (assay MGI:7493890); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: cochlear ganglion spiral ganglion neuron Present Regionally restricted S7L , S7L' Expression is seen in some, but not all, neurons.
Specimen S7M: postnatal day 10; Casz1em1Zyliu/Casz1+ (more )
Note: Triple labeled: green - Casz1 reporter; red - Map2 (assay MGI:7493890); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: vestibular ganglion neuron Present Regionally restricted S7M' , S7M Expression is seen in some, but not all, neurons.
Specimen S7N: postnatal day 21; Casz1em1Zyliu/Casz1+ (more )
Note: Triple labeled: green - Casz1 reporter; red - Map2 (assay MGI:7493890); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: cochlear ganglion spiral ganglion neuron Present Regionally restricted S7N' , S7N Expression is seen in some, but not all, neurons.
Specimen S7O: postnatal day 21; Casz1em1Zyliu/Casz1+ (more )
Note: Triple labeled: green - Casz1 reporter; red - Map2 (assay MGI:7493890); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: vestibular ganglion neuron Present Regionally restricted S7O' , S7O Expression is seen in some, but not all, neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory