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Gene Expression Data
Assay Details
Assay
Reference: J:177585 Hesse K, et al., AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483
Assay type: RNA in situ
MGI Accession ID: MGI:7492128
Gene symbol: Mef2c
Gene name: myocyte enhancer factor 2C
Probe: Mef2c probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4c Mef2c +/+ (top): embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Present 4c Mef2c +/+ (top)
TS23: midbrain Present 4c Mef2c +/+ (top)

Specimen 4c Mef2c -/- (top): embryonic day 15.5; Tfap2dtm1Mos/Tfap2dtm1Mos (more )
Structure Level Pattern Image Note
TS23: midbrain Absent 4c Mef2c -/- (top) Expression abolished in midbrain.
TS23: forebrain Present 4c Mef2c -/- (top) Expression in forebrain not altered.

Specimen 4c Mef2c +/+ (middle): embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Present 4c Mef2c +/+ (middle)
TS23: midbrain Present 4c Mef2c +/+ (middle)

Specimen 4c Mef2c -/- (middle): embryonic day 15.5; Tfap2dtm1Mos/Tfap2dtm1Mos (more )
Structure Level Pattern Image Note
TS23: midbrain Absent 4c Mef2c -/- (middle) Expression abolished in midbrain.
TS23: forebrain Present 4c Mef2c -/- (middle) Expression in forebrain not altered.

Specimen 4c Mef2c +/+ (bottom): embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Present 4c Mef2c +/+ (bottom)
TS23: midbrain Present 4c Mef2c +/+ (bottom)

Specimen 4c Mef2c -/- (bottom): embryonic day 15.5; Tfap2dtm1Mos/Tfap2dtm1Mos (more )
Structure Level Pattern Image Note
TS23: midbrain Absent 4c Mef2c -/- (bottom) Expression abolished in midbrain.
TS23: thalamus Present 4c Mef2c -/- (bottom) Expression in forebrain not altered.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory