Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Piezo1em2(cre/ERT2)Smoc
Name:	piezo-type mechanosensitive ion channel component 1; endonuclease-mediated mutation 1, Bin Zhou
MGI ID:	MGI:7491978
Synonyms:	Piezo1-CreER
Gene:	Piezo1  Location: Chr8:123208437-123278068 bp, - strand  Genetic Position: Chr8, 71.31 cM
Alliance:	Piezo1em2(cre/ERT2)Smoc page

Strain of Origin:

Not Applicable

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Piezo1em2(cre/ERT2)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Piezo1 (MGI:3603204)   Mutation details: Using CRISPR/Cas9 system, the CreERT2-P2A-BFP-WPRE-polyA was inserted after the start codon ATG of the gene Piezo1 by homologous recombination. (J:326492)

Activity:	Tissue activity of this recombinase allele
Driver:	Piezo1 (mouse) Summary of all recombinase alleles driven by Piezo1. Comparative matrix view of recombinase activities Alliance mouse Piezo1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Piezo1 Mutation:	87 strains or lines available

Original:	J:326492 Li X, et al., Generation of Piezo1-CreER transgenic mice for visualization and lineage tracing of mechanical force responsive cells in vivo. Genesis. 2022 May;60(4-5):e23476
All:	1 reference(s)