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Gene Expression Data
Assay Details
Assay
Reference: J:40032 Dou C, et al., TWH regulates the development of subsets of spinal cord neurons. Neuron. 1997 Apr;18(4):539-51
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7488699
Gene symbol: Foxb1
Gene name: forkhead box B1
Reporter: lacZ
Antibody: anti-B-galactosidase (Arnel Products)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 5B/C: embryonic day 13.5; Foxb1tm1Sli/Foxb1+ (more )
Note: Double labeled: green - Foxb1 reporter; red - Lhx3 (assay MGI:7488701).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord ventral horn spinal cord motor neuron Present Regionally restricted 5C , 5B Coexpressed with Lhx3 in a subset of cells (medial half) in the medial motor column.
Specimen 5E/F: embryonic day 13.5; Foxb1tm1Sli/Foxb1tm1Sli (more )
Note: Double labeled: green - Foxb1 reporter; red - Lhx3 (assay MGI:7488701).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord ventral horn spinal cord motor neuron Present Regionally restricted 5F , 5E Coexpressed with Lhx3 in a subset of cells (medial half) in the medial motor column, similar as in the heterozygous.
Specimen 5H/I: embryonic day 13.5; Foxb1tm1Sli/Foxb1+ (more )
Note: Double labeled: green - Foxb1 reporter; red - Lhx1 (assay MGI:7488702).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord ventral horn spinal cord motor neuron Present Regionally restricted 5H , 5I Coexpressed with Lhx1 in lateral half of the lateral motor column.
Specimen 5K/L: embryonic day 13.5; Foxb1tm1Sli/Foxb1tm1Sli (more )
Note: Double labeled: green - Foxb1 reporter; red - Lhx1 (assay MGI:7488702).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord ventral horn spinal cord motor neuron Present Regionally restricted 5K , 5L Coexpressed with Lhx1 in lateral half of the lateral motor column, similar as in the heterozygous.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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