About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:276308 Koyano-Nakagawa N, et al., Feedback Mechanisms Regulate Ets Variant 2 (Etv2) Gene Expression and Hematoendothelial Lineages. J Biol Chem. 2015 Nov 20;290(47):28107-19
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7488101
Gene symbol: Flt1
Gene name: FMS-like tyrosine kinase 1
Reporter: lacZ
Direct Detection
Results
Specimen 7Ca: embryonic day 8.75; Flt1tm1Jrt/Flt1+ (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Ca Normal vascular patterning was observed.
Specimen 7Cb: embryonic day 8.75; Flt1tm1Jrt/Flt1tm1Jrt (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Cb Excessive Flt1-LacZ-positive cells were detected. Significant vascular phenotypes were observed in the Flt1-KO.
Specimen 7Cc: embryonic day 8.75; Etv2tm1.1Djg/Etv2tm1.1Djg, Flt1tm1Jrt/Flt1tm1Jrt, Kdrtm1(cre)Sato/Kdr+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: vascular system Present 7Cc The Flt1 KO; Etv2 CKO embryos had an intermediate phenotype.
Specimen 7Cd: embryonic day 8.75; Flt1tm1Jrt/Flt1+ (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Cd Normal vascular patterning was observed.
Specimen 7Ce: embryonic day 8.75; Flt1tm1Jrt/Flt1tm1Jrt (more )
Structure Level Pattern Image Note
TS13: vascular system Present 7Ce Excessive Flt1-LacZ-positive cells were detected. Significant vascular phenotypes were observed in the Flt1-KO.
Specimen 7Cf: embryonic day 8.75; Etv2tm1.1Djg/Etv2tm1.1Djg, Flt1tm1Jrt/Flt1tm1Jrt, Kdrtm1(cre)Sato/Kdr+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: vascular system Present 7Cf The Flt1 KO; Etv2 CKO embryos had an intermediate phenotype.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory