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Gene Expression Data
Assay Details
Assay
Reference: J:309377 Betterman KL, et al., Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow. J Clin Invest. 2020 Jun 1;130(6):3315-3328
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7486777
Gene symbol: Golim4
Gene name: golgi integral membrane protein 4
Antibody: Anti-GOLPH4 antibody (ab28049)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4A: embryonic day 14.5 (more )
Note: Double labeled: green - Golim4; red - Prox1 (assay MGI:7486752).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelial cell of lymphatic vessel Present Regionally restricted 4A Expression was detected in the Golgi, located ahead of the nucleus in migrating cells.
Specimen 4B: embryonic day 14.5; Fat4tm1Hmc/Fat4tm1Hmc, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant. Double labeled: green - Golim4; red - Prox1 (assay MGI:7486752).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelial cell of lymphatic vessel Present Regionally restricted 4B Expression was detected in the Golgi, which had reduced forward positioning in the mutant compared with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory