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Gene Expression Data
Assay Details
Assay
Reference: J:238698 Kasparek P, et al., KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype. PLoS Genet. 2017 Jan;13(1):e1006566
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7484326
Gene symbol: Dsg1c
Gene name: desmoglein 1 gamma
Antibody: anti-Dsg-1
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The specificity of the antibody used was not detailed; all family members have been annotated.
Results
Specimen S8 DSG1 wt: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: epidermis Present S8_DSG1 wt

Specimen S8 DSG1 Klk5-/-;A135X/A135X: postnatal day 5; Klk5tm1Rase/Klk5tm1Rase, Spink5em1Rase/Spink5em1Rase (more )
Structure Level Pattern Image Note
TS28: epidermis Present S8_DSG1 Klk5-/-;A135X/A135X

Specimen S8 DSG1 Klk5-/-;Klk7-/-;A135X/A135X: postnatal day 5; Klk5tm1Rase/Klk5tm1Rase, Klk7em1Rase/Klk7em1Rase, Spink5em1Rase/Spink5em1Rase (more )
Structure Level Pattern Image Note
TS28: epidermis Present S8_DSG1 Klk5-/-;Klk7-/-;135X/A135X


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory