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Gene Expression Data
Assay Details
Assay
Reference: J:238698 Kasparek P, et al., KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype. PLoS Genet. 2017 Jan;13(1):e1006566
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7484320
Gene symbol: Krt14
Gene name: keratin 14
Antibody: anti-Keratin14
Detection system: Secondary antibody
Results
Specimen 5B Krt14 wt: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epidermis Present 5B Krt14 wt
Specimen 5B Krt14 A135X/A135X: embryonic day 18.5; Spink5em1Rase/Spink5em1Rase (more )
Structure Level Pattern Image Note
TS26: epidermis Strong 5B Krt14 A135X/A135X Expression increased compared to wild type.
Specimen 5B Krt14 Klk5-/-;A135X/A135X: embryonic day 18.5; Klk5tm1Rase/Klk5tm1Rase, Spink5em1Rase/Spink5em1Rase (more )
Structure Level Pattern Image Note
TS26: epidermis Present 5B Krt14 Klk5-/-;A135X/A135X Expression not altered compared to wild type
Specimen 5B Krt14 Klk7-/-;A135X/A135X: embryonic day 18.5; Klk7em1Rase/Klk7em1Rase, Spink5em1Rase/Spink5em1Rase (more )
Structure Level Pattern Image Note
TS26: epidermis Present 5B Krt14 Klk7-/-;A135X/A135X Expression not altered compared to wild type
Specimen 5B Krt14 Klk5-/-;Klk7-/-;A135X/A135X: embryonic day 18.5; Klk5tm1Rase/Klk5tm1Rase, Klk7em1Rase/Klk7em1Rase, Spink5em1Rase/Spink5em1Rase (more )
Structure Level Pattern Image Note
TS26: epidermis Present 5B Krt14 Klk5-/-;Klk7-/-;A135X/A135X Expression not altered compared to wild type
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory