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Gene Expression Data
Assay Details
Assay
Reference: J:238698 Kasparek P, et al., KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype. PLoS Genet. 2017 Jan;13(1):e1006566
Assay type: RT-PCR
MGI Accession ID: MGI:7484311
Gene symbol: Icam1
Gene name: intercellular adhesion molecule 1
Probe: Icam1-pF, Icam1-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh.
Results
Image: 7A ICAM1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
wt E18.5 TS26: back skin Weak Not Specified; total RNA Not Specified Not Specified
A135X/A135X E18.5 TS26: back skin Present (a) Not Specified; total RNA involves: C57BL/6N Spink5em1Rase/Spink5em1RaseNot Specified
Klk5-/-; A135X/A135X E18.5 TS26: back skin Weak (b) Not Specified; total RNA involves: C57BL/6N Klk5tm1Rase/Klk5tm1Rase, Spink5em1Rase/Spink5em1RaseNot Specified
Klk7-/-; A135X/A135X E18.5 TS26: back skin Weak (c) Not Specified; total RNA involves: C57BL/6N Klk7em1Rase/Klk7em1Rase, Spink5em1Rase/Spink5em1RaseNot Specified
Klk5-/-; Klk7-/-; A135X/A135X E18.5 TS26: back skin Weak (d) Not Specified; total RNA Not Specified Klk5tm1Rase/Klk5tm1Rase, Klk7em1Rase/Klk7em1Rase, Spink5em1Rase/Spink5em1RaseNot Specified
Notes:
(a) Expression levels elevated compared to wild type.
(b) Expression not upregulated compared to wild type..
(c) Expression completely normal compared to wt.
(d) Authors report full rescue of cutaneous inflammation
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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