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Gene Expression Data
Assay Details
Assay
Reference: J:256230 Shin SW, et al., Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat Commun. 2017 Nov 21;8(1):1643
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482800
Gene symbol: Dppa3
Gene name: developmental pluripotency-associated 3
Antibody: Anti-STELLAR antibody ab19878
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen S1e Fertilization 1C: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted S1e (left) 1C , S1e (left) 1C Merge Expression in pronuclei and cytoplasm of fertilized 1-cell zygotes.
Specimen S1e Fertilization 2C: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Weak Regionally restricted S1e (left) 2C , S1e (left) 2C Merge Less robust expression in 2-cell embryos.
Specimen S1e Fertilization 4C: embryonic day 2.0 (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Trace Regionally restricted S1e (left) 4C , S1e (left) 4C Merge Only faint expression in nuclei of 4-cell embryos.
Specimen S7a DPPA3 WT: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted S7a WT DPPA3 Merge , S7a WT DPPA3 Expression in cytoplasm and pronuclei.
Specimen S7A DPPA3 R60A/-: embryonic day 0.5; Dppa3em1Dean/Dppa3tm1Masu (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted S7a R60A/- DPPA3 Merge , S7a R60A/- DPPA3 Expression strongly localized in both pronuclei, but absent from cytoplasm.
Specimen S7A DPPA3 -/-: embryonic day 0.5; Dppa3tm1Masu/Dppa3tm1Masu (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Absent S7a -/- Merge , S7a -/- DPPA3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory