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Gene Expression Data
Assay Details
Assay
Reference: J:126484 Luo W, et al., A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7481303
Gene symbol: P2rx3
Gene name: purinergic receptor P2X, ligand-gated ion channel, 3
Antibody: anti-P2RX3
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 3I: postnatal day 14; Rettm1Ddg/Rettm1Ddg (more )
Note: Double labeled: red - P2rx3; green - Prph (assay MGI:7481299).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present 3I inset , 3I
Specimen 3J: postnatal day 14; Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - P2rx3; green - Prph (assay MGI:7481299).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 3J , 3J inset Similar number of double-labeled neurons. Significantly smaller soma size compared to control.
Specimen 6I: postnatal day 14; Rettm1Ddg/Rettm1Ddg (more )
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 6I Expression in ~105 neurons/section.
Specimen 6J: postnatal day 14; Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 6J Number of double-labeled neurons similar to control. Expression in ~110 neurons/section.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory