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Gene Expression Data
Assay Details
Assay
Reference: J:126484 Luo W, et al., A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7481299
Gene symbol: Prph
Gene name: peripherin
Antibody: anti-peripherin
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3C: postnatal day 14; Rettm1Ddg/Rettm1Ddg (more )
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present 3C
Specimen 3D: postnatal day 14; Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 3D Hypotrophic neuronal soma in most expressing neurons. 47.3% reduction in soma area compared to control.
Specimen 3I: postnatal day 14; Rettm1Ddg/Rettm1Ddg (more )
Note: Double labeled: green - Prph; red - P2rx3 (assay MGI:7481303).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present 3I inset , 3I
Specimen 3J: postnatal day 14; Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - Prph; red - P2rx3 (assay MGI:7481303).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 3J inset , 3J Number of double-labeled neurons similar to control, but expressing cells with significantly smaller soma size compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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