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Gene Expression Data
Assay Details
Assay
Reference: J:126484 Luo W, et al., A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
Assay type: RNA in situ
MGI Accession ID: MGI:7481269
Gene symbol: Gfra1
Gene name: glial cell line derived neurotrophic factor family receptor alpha 1
Probe: Gfra1 probe
Probe preparation: labelled with digoxigenin RNA
Results
Specimen S1A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Absent S1A
Specimen S1B: embryonic day 16.0 (more )
Structure Cell Type Level Pattern Image Note
TS24: dorsal root ganglion sensory neuron of dorsal root ganglion Present Single cells S1B Expression first observed in small subset of neurons at E16.
Specimen S1C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dorsal root ganglion Present Regionally restricted S1C ilar expression pattern at P0 and P10.
Specimen S1D: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Regionally restricted S1D ilar expression pattern at P0 and P10.
Specimen 2C: postnatal day 0; Baxtm1Sjk/Baxtm1Sjk, Ngftm1Gne/Ngf+ (more )
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 2C Expresssion in 12.2% of neurons.
Specimen 2D: postnatal day 0; Baxtm1Sjk/Baxtm1Sjk, Ngftm1Gne/Ngftm1Gne (more )
Structure Level Pattern Image Note
TS27: dorsal root ganglion Absent 2D Expression completely eliminated.
Specimen 5A: postnatal day 10; Rettm1Ddg/Rettm1Ddg (more )
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 5A Expression in ~26 neurons/section.
Specimen 5B: postnatal day 10; Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Weak Regionally restricted 5B Significant redcution in number of expressing neurons. Expression in ~9 neurons/section.
Specimen S6A: postnatal day 2; Rettm1Ddg/Rettm1Ddg (more )
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present S6A
Specimen S6B: postnatal day 2; Rettm1Ddg/Rettm1Ddg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: spinal cord ventral horn sensory neuron of dorsal root ganglion Present Regionally restricted S6B Significant reduction in number of expressing neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory