Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Krt6aem1(icre)Vk
Name:	keratin 6A; endonuclease-mediated mutation 1, Vesa Kaartinen
MGI ID:	MGI:7464182
Synonyms:	Krt6aiCre
Gene:	Krt6a  Location: Chr15:101598363-101602740 bp, - strand  Genetic Position: Chr15, 56.97 cM
Alliance:	Krt6aem1(icre)Vk page

Strain of Origin:

C57BL/6 x SJL

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Krt6aem1(icre)Vk expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Krt6a (MGI:1100845)   Mutation details: CRISPR/Cas9 genome editing is used to introduce the iCre-pA cassettes at the Krt6a initiator methionine site in exon 1. (J:325729, J:334621)

Activity:	Tissue activity of this recombinase allele
Driver:	Krt6a (mouse) Summary of all recombinase alleles driven by Krt6a. Comparative matrix view of recombinase activities Alliance mouse Krt6a gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt6a Mutation:	25 strains or lines available

Original:	J:334621 Saroya G, et al., Periderm Fate during Palatogenesis: TGF-beta and Periderm Dedifferentiation. J Dent Res. 2023 Apr;102(4):459-466
All:	2 reference(s)