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Gene Expression Data
Assay Details
Assay
Reference: J:314694 Douchi D, et al., Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus. Gastroenterology. 2021 Dec;161(6):1907-1923.e26
Assay type: RNA in situ
MGI Accession ID: MGI:7463963
Gene symbol: Pgc
Gene name: progastricsin (pepsinogen C)
Probe: Mm-Pgc (519461)
Probe preparation: Antisense
Visualized with: Chromogenic
Assay notes: RNAscope assay.
Results
Specimen S1J: postnatal adult (more )
Note: Double labeled: blue - Pgc; red - Mki67 (assay MGI:7463941).
Structure Cell Type Level Pattern Image Note
TS28: stomach glandular region gastric gland Present Non-Uniform S1J , S1J Isthmus , S1J Base Although the most expression is seen in the base of the corpus unit, expression is also seen in neck and isthmus cells.
TS28: stomach glandular region epithelium peptic cell Present S1J Base , S1J Expression is seen in chief cells.
Specimen S2D: postnatal adult; Pgctm1.1(cre/ERT2)Itoy/Pgc+ (more )
Note: Double labeled: blue - Pgc; red - Mki67 (assay MGI:7463941).
Structure Cell Type Level Pattern Image Note
TS28: stomach glandular region gastric gland Present Non-Uniform S2D Isthmus , S2D Base , S2D Expression is seen in base and isthmus cells of the corpus unit.
TS28: stomach glandular region epithelium peptic cell Present S2D Base , S2D Expression is seen in chief cells.
Specimen S7A: postnatal adult (more )
Note: Double labeled: blue - Pgc; red - Iqgap3 (assay MGI:7463965).
Structure Level Pattern Image Note
TS28: stomach glandular region gastric gland Present S7A Base , S7A Isthmus , S7A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory