Pgc In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:314694 Douchi D, et al., Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus. Gastroenterology. 2021 Dec;161(6):1907-1923.e26
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:7461913
Gene symbol:	Pgc
Gene name:	progastricsin (pepsinogen C)

Reporter:	Cre
Antibody:	anti-cre (Novus Biologicals)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

S2G left ©

S2G right ©

Specimen S2G: postnatal adult; Pgc^{tm1.1(cre/ERT2)Itoy}/Pgc⁺ (more

)
Note: Triple labeled: green - Pgc reporter (Cre); red - Pgc reporter (mCherry; assay MGI:7461884); blue - Mki67 (assay MGI:7463939).

Structure	Level	Pattern	Image	Note
TS28: stomach glandular region gastric gland	Present	Non-Uniform	S2G left , S2G right	There is expression in the gland base of the corpus. Cre was expressed in most mCherry-expressing cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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