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Gene Expression Data
Assay Details
Assay
Reference: J:229467 Zhang KK, et al., Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation. Hum Mol Genet. 2016 Mar 15;25(6):1140-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7461783
Gene symbol: Pcsk6
Gene name: proprotein convertase subtilisin/kexin type 6
Antibody: anti-PACE4 (ab140934)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 6D/6E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: secondary heart field Strong 6D , 6E Strong expression within dorsal mesocardium at inflow region (posterior second heart field, pSHF).

Specimen 6F/6G: embryonic day 9.5; Tbx5tm1.1Jse/Tbx5+ (more )
Structure Level Pattern Image Note
TS15: secondary heart field Weak 6G , 6F Expression significantly decreased compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory