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Gene Expression Data
Assay Details
Assay
Reference: J:334332 Pilaz LJ, et al., Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development. Neuron. 2023 Mar 15;111(6):839-856.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7461494
Gene symbol: Arhgap11a
Gene name: Rho GTPase activating protein 11A
Antibody: anti-ARHGAP11A (A303-097A)
Assay notes: Two Arhgap11a antibodies were described, but the one used in this assay was not detailed. Anti-Arhgap11a (ab113261) MGI:7461491 may have been used in this assay.
Results
Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon ventricular layer Present Regionally restricted 1E ARHGAP11A Expression localized within germinal zones.

Specimen 1F: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex marginal layer forebrain radial glial cell Present Regionally restricted 1F ARHGAP11A Expression enriched near pial surface at presumptive radial glial cell endfeet and along basal processes.

Specimen 1G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present Regionally restricted 1G ARHGAP11A Localization near pial surface especially visible at later stages.

Specimen 1H ARHGAP11A: embryonic day 15.5 (more )
Note: Double labeled: red - Arhgap11a; green - Nes (assay MGI:7461495).
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex marginal layer forebrain radial glial cell Present Regionally restricted 1H Merge , 1H ARHGAP11A Expression overlapping with Nestin expression in basal process and endfeet at pial surface.

Specimen 1M ARHGAP11A IF: embryonic day 16.5 (more )
Note: Double labeled: green - Arhgap11a protein; red - Arhgap11a RNA (assay MGI:7461498).
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex marginal layer forebrain radial glial cell Present Regionally restricted 1M inset , 1M Expression in radial glial cell endfeet at pia, colocalizing with Arhgap11a mRNA expression.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory