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Gene Expression Data
Assay Details
Assay
Reference: J:278094 Pu W, et al., Genetic Targeting of Organ-Specific Blood Vessels. Circ Res. 2018 Jun 22;123(1):86-99
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7451396
Gene symbol: Cdh5
Gene name: cadherin 5
Antibody: anti-VE-cadherin (AF1002)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen Online IIID: postnatal day 0; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS27: heart blood vessel blood vessel endothelial cell Present Online IIID Magnification , Online IIID
Specimen Online IIIE: postnatal day 0; Gt(ROSA)26Sortm66.2(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS27: liver vasculature blood vessel endothelial cell Present Online IIIE , Online IIIE Magnification
Specimen 2D: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: heart blood vessel blood vessel endothelial cell Present 2D CDH5 , 2D Merge inset , 2D Merge , 2D CDH5 inset
Specimen 2E - Brain: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 2E Brain , Online IV_Brain , Online IV_Brain Magnification
Specimen 2E - Lung: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element blood vessel endothelial cell Present Online IV_Lung , 2E Lung , Online IV_Lung Magnification
Specimen 2E - Liver: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: liver vasculature blood vessel endothelial cell Present Online IV_Liver Magnification , 2E Liver , Online IV_Liver
Specimen 2E - Muscle: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: muscle blood vessel blood vessel endothelial cell Present Online IV_Muscle , Online IV_Muscle Magnification , 2E Muscle
Specimen 2E - Spleen: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: spleen vascular element blood vessel endothelial cell Present 2E Spleen , Online IV_Spleen , Online IV_Spleen Magnification
Specimen 2E - Pancreas: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: pancreas vasculature blood vessel endothelial cell Present Online IV_Pancreas Magnification , Online IV_Pancreas , 2E Pancreas
Specimen 2E - Stomach: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: stomach vascular element blood vessel endothelial cell Present Online IV_Stomach Magnification , 2E Stomach , Online IV_Stomach
Specimen 2E - Intestine: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: intestine vascular element blood vessel endothelial cell Present 2E Intestine , Online IV_Intestine Magnification , Online IV_Intestine
Specimen 2E - Skin: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present Online IV_Skin Magnification , 2E Skin , Online IV_Skin
Specimen 2E - Bladder: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: vasculature of bladder blood vessel endothelial cell Present Online IV_Bladder Magnification , 2E Bladder , Online IV_Bladder
Specimen 2E - Kidney: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: renal vasculature blood vessel endothelial cell Present Online IV_Kidney Magnification , 2E Kidney , Online IV_Kidney
Specimen 2E - Thymus: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: thymus blood vessel blood vessel endothelial cell Present Online IV_Thymus Magnification , Online IV_Thymus , 2E Thymus
Specimen Online VB: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: heart blood vessel blood vessel endothelial cell Present Online VB CDH5 , Online VB Merge
Specimen Online VC - Liver: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: liver vasculature blood vessel endothelial cell Present Online VC Liver
Specimen Online VC - Brain: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present Online VC Brain
Specimen Online VC - Pancreas: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: pancreas vasculature blood vessel endothelial cell Present Online VC Pancreas
Specimen Online VC - Muscle: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: muscle blood vessel blood vessel endothelial cell Present Online VC Muscle
Specimen Online VC - Thymus: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: thymus blood vessel blood vessel endothelial cell Present Online VC Thymus
Specimen Online VC - Intestine: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: intestine vascular element blood vessel endothelial cell Present Online VC Intestine
Specimen Online VC - Stomach: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: stomach vascular element blood vessel endothelial cell Present Online VC Stomach
Specimen Online VC - Skin: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present Online VC Skin
Specimen Online VC - Bladder: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: vasculature of bladder blood vessel endothelial cell Present Online VC Bladder
Specimen Online VC - Kidney: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: renal vasculature blood vessel endothelial cell Present Online VC Kidney
Specimen Online VC - Lung: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element blood vessel endothelial cell Present Online VC Lung
Specimen Online VC - Spleen: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: spleen vascular element blood vessel endothelial cell Present Online VC Spleen
Specimen Online VE: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: heart blood vessel blood vessel endothelial cell Present Online VE CDH5 , Online VE Merge
Specimen Online VF - Liver: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: liver vasculature blood vessel endothelial cell Present Online VF Liver
Specimen Online VF - Brain: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present Online VF Brain
Specimen Online VF - Pancreas: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: pancreas vasculature blood vessel endothelial cell Present Online VF Pancreas
Specimen Online VF - Muscle: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: muscle blood vessel blood vessel endothelial cell Present Online VF Muscle
Specimen Online VF - Thymus: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: thymus blood vessel blood vessel endothelial cell Present Online VF Thymus
Specimen Online VF - Intestine: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: intestine vascular element blood vessel endothelial cell Present Online VF Intestine
Specimen Online VF - Stomach: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: stomach vascular element blood vessel endothelial cell Present Online VF Stomach
Specimen Online VF - Skin: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present Online VF Skin
Specimen Online VF - Bladder: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: vasculature of bladder blood vessel endothelial cell Present Online VF Bladder
Specimen Online VF - Kidney: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: renal vasculature blood vessel endothelial cell Present Online VF Kidney
Specimen Online VF - Lung: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element blood vessel endothelial cell Present Online VF Lung
Specimen Online VF - Spleen: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: spleen vascular element blood vessel endothelial cell Present Online VF Spleen
Specimen 3B - Control: embryonic day 14.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Kdrtm1Wag/Kdr+, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Triple labeled: gray - Cdh5; green - Kdr (assay MGI:7460310); red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS22: heart endothelium cardiac endothelial cell Present 3B Merge Control , 3B CDH5 Control
Specimen 3B - Mutant: embryonic day 14.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Kdrtm1Wag/Kdrtm1Wag, Tekem1(dre)Bzsh/Tek+, Wt1em1(cre/ERT2)Bzsh/Wt1+ (more )
Note: Conditional mutant. Triple labeled: gray - Cdh5; green - Kdr (assay MGI:7460310); red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS22: heart endothelium cardiac endothelial cell Present 3B Merge Mutant , 3B CDH5 Mutant
Specimen Online VIIIA: postnatal adult; Mfsd2aem1(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - Mfsd2a reporter (assay MGI:7446568).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present Online VIIIA Merge , Online VIIIA CDH5 Expression is seen in endothelial cells of the blood-brain barrier.
Specimen Online IXD - left: postnatal adult; Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - Mfsd2a reporter (assay MGI:7460354).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present Online IXC left , Online IXC Magnification left Expression is seen in endothelial cells of the blood-brain barrier.
Specimen Online IXE - Heart: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: heart blood vessel blood vessel endothelial cell Present Online IXE Heart
Specimen Online IXE - Liver: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: liver vasculature blood vessel endothelial cell Present Online IXE Liver
Specimen Online IXE - Brain: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present Online IXE Brain
Specimen Online IXE - Kidney: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: renal vasculature blood vessel endothelial cell Present Online IXE Kidney
Specimen Online IXE - Lung: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element blood vessel endothelial cell Present Online IXE Lung
Specimen Online IXE - Stomach: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: stomach vascular element blood vessel endothelial cell Present Online IXE Stomach
Specimen Online IXE - Muscle: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: muscle blood vessel blood vessel endothelial cell Present Online IXE Muscle
Specimen Online IXE - Thymus: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: thymus blood vessel blood vessel endothelial cell Present Online IXE Thymus
Specimen Online IXE - Intestine: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: intestine vascular element blood vessel endothelial cell Present Online IXE Intestine
Specimen Online IXE - Spleen: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: spleen vascular element blood vessel endothelial cell Present Online IXE Spleen
Specimen Online IXE - Pancreas: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: pancreas vasculature blood vessel endothelial cell Present Online IXE Pancreas
Specimen Online IXE - Skin: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+ (more )
Note: Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present Online IXE Skin
Specimen 4D - upper right: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 4D upper right , 4D upper right Magnification
Specimen 4F: postnatal adult; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 4F Expression is seen in large blood vessels.
Specimen Online XID - Brain: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present Online XID Brain
Specimen Online XID - Heart: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: heart blood vessel blood vessel endothelial cell Present Online XID Heart
Specimen Online XID - Lung: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: lung vascular element blood vessel endothelial cell Present Online XID Lung
Specimen Online XID - Liver: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: liver vasculature blood vessel endothelial cell Present Online XID Liver
Specimen Online XID - Kidney: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: renal vasculature blood vessel endothelial cell Present Online XID Kidney
Specimen Online XID - Skeletal muscle: postnatal week 6; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Double labeled: green - Cdh5; red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS28: muscle blood vessel blood vessel endothelial cell Present Online XID Skeletal muscle
Specimen 5B - Control: postnatal day 0; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Kdrtm1Wag/Kdr+, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Triple labeled: gray - Cdh5; green - Kdr (assay MGI:7460310); red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS27: brain blood vessel blood vessel endothelial cell Present 5B CDH5 Control , 5B Merge Control , 5B Magnification Control
Specimen 5B - Mutant: postnatal day 0; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Kdrtm1Wag/Kdrtm1Wag, Mfsd2aem2(cre/ERT2)Bzsh/Mfsd2a+, Tekem1(dre)Bzsh/Tek+ (more )
Note: Conditional mutant. Triple labeled: gray - Cdh5; green - Kdr (assay MGI:7460310); red - recombinase reporter.
Structure Cell Type Level Pattern Image Note
TS27: brain blood vessel blood vessel endothelial cell Present 5B CDH5 Mutant , 5B Merge Mutant , 5B Magnification Mutant Vessel density is significantly reduced in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory