Gt(ROSA)26Sor^{tm66.2(CAG-tdTomato)Hze}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm66.2(CAG-tdTomato)Hze}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 66.2, Hongkui Zeng
• MGI ID: MGI:6357184
• Synonyms: Rosa26-Rox-Stop-Rox-tdTomato, Rosa26-RSR-tdTomato
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm66.2(CAG-tdTomato)Hze} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236001
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Mice with Gt(ROSA)26Sor^{tm66.1(CAG-tdTomato)Hze} allele were crossed with Cre-deleter mice to remove loxP-flanked STOP. The Cre transgene was not passaged to the subsequent generation. After removal of the Rox flanked STOP cassettes by Dre-recombination, tdTomato fluorescence is expected in cells/tissues expressing Dre recombinase. (J:236001)

Expression

In Mice Carrying this Mutation:

39 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:236001 Zhang H, et al., Endocardium Contributes to Cardiac Fat. Circ Res. 2016 Jan 22;118(2):254-65
• All: 22 reference(s)