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Gene Expression Data
Assay Details
Assay
Reference: J:267540 Cesario JM, et al., Anti-osteogenic function of a LIM-homeodomain transcription factor LMX1B is essential to early patterning of the calvaria. Dev Biol. 2018 Nov 15;443(2):103-116
Assay type: RNA in situ
MGI Accession ID: MGI:7449170
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3G/J/M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: frontal bone primordium Present 3J , 3M , 3G No expression in the early migrating mesenchyme.
Specimen 3S: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: frontal bone primordium Present 3S
Specimen 5A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: head mesenchyme Absent 5A
Specimen 5B: embryonic day 14.5; Lmx1btm1Rjo/Lmx1btm1Zfc, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: head mesenchyme Present Regionally restricted 5B Ectopically expressed in the vertex.
Specimen 7C: embryonic day 12.5; Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS20: cranium bone primordium Present Regionally restricted 7C Expressed in the parietal bone primordium.
Specimen 7D: embryonic day 12.5; Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cranium bone primordium Weak Regionally restricted 7D Very weakly expressed at the equivalent position within supra-orbital mesenchyme.
Specimen 7I: embryonic day 14.5; Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS22: parietal bone primordium Present 7I
Specimen 7J: embryonic day 14.5; Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: parietal bone primordium Absent 7J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory