About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:316179 Wang A, et al., An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7444001
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Results
Specimen S4A Ki67 WT: embryonic day 15.5 (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS23: neocortex Present S4A WT Ki67 , S4A WT (enlarged) , S4A WT BrdU/Ki67 (upper) , S4A WT BrdU/Ki67 (lower)
Specimen S4A Ki67 KO: embryonic day 15.5; Lncbarem1Bcgen/Lncbarem1Bcgen (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted S4A KO Ki67 , S4A KO BrdU/Ki67 (lower) , S4A KO (enlarged) , S4A KO BrdU/Ki67 (upper) Smaller proportion BrdU-labeled cells co-expressing Mki67
Specimen 3A Ki67 WT: embryonic day 16.5 (more )
Note: Triple labeled: blue/green - Mki67; red - Tbr2 (Eomes assay MGI:7444000); green - BrdU.
Structure Level Pattern Image Note
TS24: neocortex Present 3A WT TBR2/Ki67 , 3A WT TBR2/BrdU/Ki67 (enlarged) , 3A WT TBR2/BrdU/Ki67 (upper) , 3A WT TBR2/BrdU/Ki67 (lower)
Specimen 3A Ki67 KO: embryonic day 16.5; Lncbarem1Bcgen/Lncbarem1Bcgen (more )
Note: Triple labeled: blue/green - Mki67; red - Tbr2 (Eomes assay MGI:7444000); green - BrdU.
Structure Level Pattern Image Note
TS24: neocortex Weak 3A KO TBR2/BrdU/Ki67 (lower) , 3A KO TBR2/BrdU/Ki67 (enlarged) , 3A KO TBR2/Ki67 , 3A KO TBR2/BrdU/Ki67 (upper) Fewer expressing cells compared to control. Fewer triple-labeled cells
Specimen S4E Ki67 WT: embryonic day 13.5 (more )
Note: Triple labeled: blue/green - Mki67; red - Tbr2 (Eomes assay MGI:7444000); green - BrdU.
Structure Level Pattern Image Note
TS21: neocortex Present S4E WT TBR2/BrdU/Ki67 , S4E WT Merge , S4E WT TBR2/Ki67
Specimen S4E Ki67 KO: embryonic day 13.5; Lncbarem1Bcgen/Lncbarem1Bcgen (more )
Note: Triple labeled: blue/green - Mki67; red - Tbr2 (Eomes assay MGI:7444000); green - BrdU.
Structure Level Pattern Image Note
TS21: neocortex Present Regionally restricted S4E KO TBR2/BrdU/Ki67 , S4E KO Merge , S4E KO TBR2/Ki67 Significantly more cells co-expressing Tbr2 (Eomes).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory