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Gene Expression Data
Assay Details
Assay
Reference: J:294158 Vernersson Lindahl E, et al., An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71
Assay type: Western blot
MGI Accession ID: MGI:7438152
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: anti-p63 (sc-8431)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 4c
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Size Not Specified (b) Size Not Specified (c) Size Not Specified (d) Genetic BackgroundMutant Allele(s)Sex
p63R279HN/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd Trp63tm3Aam/Trp63+Not Specified
p63+/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd Not Specified
p63+/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd Not Specified
p63R279HN/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd Trp63tm3Aam/Trp63+Not Specified
p63R279HN/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd Trp63tm3Aam/Trp63+Not Specified
p63R279HN/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd Trp63tm3Aam/Trp63+Not Specified
deltaNp63alpha Control
p63+/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd * BALB/c * C57BL/6 Not Specified
p63R279H/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd * BALB/c * C57BL/6 Trp63tm3.1Aam/Trp63+Not Specified
p63R279H/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd * BALB/c * C57BL/6 Trp63tm3.1Aam/Trp63+Not Specified
p63R279H/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd * BALB/c * C57BL/6 Trp63tm3.1Aam/Trp63+Not Specified
p63R279H/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd * BALB/c * C57BL/6 Trp63tm3.1Aam/Trp63+Not Specified
p63+/+ P newborn TS27: epidermis Present Present Present Present involves: 129S7/SvEvBrd * BALB/c * C57BL/6 Not Specified
Notes:
(a) Trp63 protein accumulated specifically in the R279HN/+ epidermis compared to wild type and R279H/+ epidermis.
(b) deltaNp63 alpha isoform. This isoform was specifically upregulated in the R279HN/+ mice.
(c) deltaNp63 beta isoform. This isoform was specifically upregulated in the R279HN/+ mice.
(d) deltaNp63 gamma isoform. This isoform was specifically upregulated in the R279HN/+ mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory