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Gene Expression Data
Assay Details
Assay
Reference: J:333188 Koizumi M, et al., UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death. FASEB J. 2022 Dec;36(12):e22662
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437674
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-Eomes/Tbr2 (ab23345)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-TBR2 MGI:6153996 may have been used in this assay.
Results
Specimen 5B Utx flox/flox: embryonic day 12.5; Kdm6atm1.1Homy/Kdm6atm1.1Homy (more )
Structure Cell Type Level Pattern Image Note
TS20: brain neural progenitor cell Present 5B Utx flox/flox Merge , 5B Utx flox/flox TBR2 Expression in intermediate progenitor cells.

Specimen 5B Utx delta/delta: embryonic day 12.5; Kdm6atm1.1Homy/Kdm6atm1.1Homy, Sox1tm1(cre)Take/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: brain neural progenitor cell Present 5B Utx delta/delta Merge , 5B Utx delta/delta TBR2 Percentage of expressing cells sidnificantly lower than control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory