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Gene Expression Data
Assay Details
Assay
Reference: J:237224 Kim JY, et al., Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437614
Gene symbol: Pals1
Gene name: protein associated with LIN7 1, MAGUK family member
Antibody: Pals1 antibody (07-708)
Detection system: Secondary antibody coupled to Cy5
Results
Specimen 5F: embryonic day 15.5; Tg(rx3-icre)1Mjam/0, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Double labeled: red - Pals1; green - Yap1 (assay MGI:7437575).
Structure Level Pattern Image Note
TS23: neural retina Present Regionally restricted 5F , 5F3 , 5F1 The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. There was partial fusion when the duplicated retina abutted the original retina.
TS23: pigmented retinal epithelium Present Regionally restricted 5F , 5F3 , 5F1 The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. There was partial fusion when the duplicated retina abutted the original retina.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory