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Gene Expression Data
Assay Details
Assay
Reference: J:333149 Zhao T, et al., Sertoli cell PUMILIO proteins modulate mouse testis size through translational control of cell cycle regulators. Biol Reprod. 2022 Jul 25;107(1):135-147
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437574
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: Anti-Sox9 (AB5535)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixation was with Hartman's fixative.
Results
Specimen 3A E17.5 Control: embryonic day 17.5; Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Present 3A E17.5 Control

Specimen 3A E17.5 AcP1KO: embryonic day 17.5; Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Present 3A E17.5 AcP1KO Number of expressing cells significanly reduced compared to control.

Specimen 3A P14 Control: postnatal day 14; Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 3A P14 Control

Specimen 3A P14 AcP1KO: postnatal day 14; Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 3A P14 AcP1KO Number of expressing cells significanly reduced compared to control.

Specimen 3A Adult Control: postnatal adult; Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 3A Adult Control

Specimen 3A Adult AcP1KO: postnatal adult; Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 3A Adult AcP1KO Number of expressing cells significanly reduced compared to control.

Specimen 5E SOX9 Control: postnatal day 14; Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 5E SOX9 Control

Specimen 5E SOX8 AcP1KO: postnatal day 14; Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 5E SOX9 AcP1KO

Specimen 5E SOX8 AcP1KO; Cdkn1b+/-: postnatal day 14; Cdkn1btm1Mlf/Cdkn1b+, Plekha5Tg(AMH-cre)1Flor/0, Pum1tm1.1Eyx/Pum1tm1.1Eyx (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 5E SOX9 AcP1KO; Cdnk1b+/-


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory